De Ritis score as an inflammatory marker in Hashimoto's thyroiditis

Background The aim of the study was assessing De Ritis score, an inflammatory marker, in Hashimoto's thyroiditis (HT) patients which is characterized with autoimmunity and chronic inflammation. Methods Between October 2021 2022, subjects our outpatient clinics diagnosed healthy controls enrolled to study. Age, gender, laboratory parameters including C-reactive protein (CRP), alanine (ALT), aspartate (AST) transaminases, thyroid stimulating hormone (TSH), free T4 (FT4), were obtained recorded for all participants, retrospectively. Division AST by ALT formula calculate score. Characteristics data compared. Results Median de ratio HT group (1.11 (0.56)%) significantly higher than that control (0.91 (0.41)%), (p < .001). A positive significant correlation between score CRP (r = 0.46, p .001) values. ROC analysis revealed sensitivity specificity predicting those 0.9% has 67% 50% selecting (AUC: 0.69, .001, 95% CI: 0.63–0.76). Conclusions We think elevated can be used as adjunctive tool diagnosis HT.